The article analyzes the main stages of the national structure`s evolution of the region at the beginning of the foundation of Saratov to its radical transformation at the beginning of the third millennium. The problem of «new» ethnic groups in the modern development of a regional multinational community is considered. On the example of the system`s formation of ethno-confessional cooperation in the Saratov Region, the regularities and distinctive features of the Russian «imperialism» are determined.